Intracytoplasmic sperm injection (ICSI)

Intracytoplasmic sperm injection (ICSI) is a highly technical fertility treatment where a single sperm is injected into the centre of each egg to try to achieve fertilisation. We were the first NHS unit in the country to have a baby born from the intracytoplasmic sperm injection technique.

What does ICSI involve?

Stimulation and egg collection in an ICSI cycle are the same as in an IVF cycle, except in an ICSI cycle, mature eggs are directly injected with sperm instead of being placed together in a dish.

ICSI might help if:

  • the sperm sample contains decreased numbers of sperm, reduced movement, or the sperm shows a high number display or an abnormal appearance
  • the male partner has no sperm in his ejaculate, but sperm can be obtained from the testicles using surgery
  • the male partner produces high levels of antibodies against his sperm – this can affect the ability of the sperm to bind to the egg
  • couples have already had IVF treatment but had unexplained failed fertilisation of all the eggs
  • the male partner has retrograde ejaculation – the sperm passes back into the bladder and can be found in the urine.

How successful are IVF and ICSI?

On average, we expect 50% of couples to achieve a positive pregnancy test and 33% to have a baby, but the success is highly dependent on the age of the woman. These results compare favourably with those from other centres in the UK and worldwide.


In-vitro fertilisation

Access private IVF treatment from fertility specialists in the heart of London.

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Frozen embryo transfer

During ICSI treatment it is possible to freeze embryos not used in that cycle for future use.

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Private fertility pricing and packages

We offer a range of funding options for our world-leading fertility services and treatments.

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